Alignment to California Standards
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Biology/Life Sciences
Grades Nine Through Twelve Science Content Standards


URL of standards: http://www.cde.ca.gov/be/st/ss/scbiology.asp (updated 07/21/2006)

Standards that all students are expected to achieve in the course of their studies are unmarked. Standards that all students should have the opportunity to learn are marked with an asterisk (*).

KEY: SB1 = Senior Biology 1 SB2 = Senior Biology 2


Cell Biology
1. The fundamental life processes of plants and animals depend on a variety of chemical reactions that occur in specialized areas of the organism's cells. As a basis for understanding this concept:
P.O. Book & Chapter page no.s
a. Students know cells are enclosed within semipermeable membranes that regulate their interaction with their surroundings. SB1: The Chemistry of Life 69-72
SB1: Cell Membranes & Transport 113-116, 119-122, 125-126
SB2: Gas Exchange in Animals 189-191
b. Students know enzymes are proteins that catalyze biochemical reactions without altering the reaction equilibrium and the activities of enzymes depend on the temperature, ionic conditions, and the pH of the surroundings.
SB1: The Chemistry of Life 69-72
c. Students know how prokaryotic cells, eukaryotic cells (including those from plants and animals), and viruses differ in complexity and general structure.
SB1: Cell Structure 81, 87-94, 96, 107-108
SB1:Classification 337
SB2: Pathogens & Disease 22
d. Students know the central dogma of molecular biology outlines the flow of information from transcription of ribonucleic acid (RNA) in the nucleus to translation of proteins on ribosomes in the cytoplasm.
SB1: Molecular Genetics 143-146, 157-158, 161-164
e. Students know the role of the endoplasmic reticulum and Golgi apparatus in the secretion of proteins.
SB1: Cell Membranes & Transport 112, 115-118
f. Students know usable energy is captured from sunlight by chloroplasts and is stored through the synthesis of sugar from carbon dioxide. SB1: Cellular Energetics 129, 136-140
SB2: Plant Structure & Adaptation 340, 354
g. Students know the role of the mitochondria in making stored chemical-bond energy available to cells by completing the breakdown of glucose to carbon dioxide.
SB1: Cellular Energetics 130-134
h. Students know most macromolecules (polysaccharides, nucleic acids, proteins, lipids) in cells and organisms are synthesized from a small collection of simple precursors.
SB1: The Chemistry of Life 58-68
SB1: Molecular Genetics 143-144
i.* Students know how chemiosmotic gradients in the mitochondria and chloroplast store energy for ATP production.
SB1: Cellular Energetics 133-134, 137-138
j* Students know how eukaryotic cells are given shape and internal organization by a cytoskeleton or cell wall or both.
SB1: Cell Structure 89-92
SB1: Cell Membranes & Transport 115-116
SB2: Plant Structure & Adaptation 337-338
 
Genetics
2. Mutation and sexual reproduction lead to genetic variation in a population. As a basis for understanding this concept:
P.O. Book & Chapter page no.s
a. Students know meiosis is an early step in sexual reproduction in which the pairs of chromosomes separate and segregate randomly during cell division to produce gametes containing one chromosome of each type.
SB1: Genes & Chromosomes 181-184
b. Students know only certain cells in a multicellular organism undergo meiosis.
SB1: Genes & Chromosomes 181-182
c. Students know how random chromosome segregation explains the probability that a particular allele will be in a gamete.
SB1: Cell Structure 99
SB1: Genes & Chromosomes 177-178, 181-182
SB1: Inheritance 208
d. Students know new combinations of alleles may be generated in a zygote through the fusion of male and female gametes (fertilization).
SB1: Inheritance 208-210
e. Students know why approximately half of an individual's DNA sequence comes from each parent. SB1: Cell Structure 99
SB2: Reproduction & Development 229, 241-242
f. Students know the role of chromosomes in determining an individual's sex.
SB1: Genes & Chromosomes 169-170
SB1: Inheritance 217
g. Students know how to predict possible combinations of alleles in a zygote from the genetic makeup of the parents.
SB1: Inheritance 209-210, 215-216
 
3. A multicellular organism develops from a single zygote, and its phenotype depends on its genotype, which is established at fertilization</span><span >. As a basis for understanding this concept:
P.O. Book & Chapter page no.s
a. Students know how to predict the probable outcome of phenotypes in a genetic cross from the genotypes of the parents and mode of inheritance (autosomal or X-linked, dominant or recessive). SB1: Inheritance 211-212, 225-227
b. Students know the genetic basis for Mendel's laws of segregation and independent assortment. SB1: Inheritance 207-208
c.* Students know how to predict the probable mode of inheritance from a pedigree diagram showing phenotypes.
SB1: Inheritance 228-229
d.* Students know how to use data on frequency of recombination at meiosis to estimate genetic distances between loci and to interpret genetic maps of chromosomes.
SB1: Genes & Chromosomes 187-188
 
4. Genes are a set of instructions encoded in the DNA sequence of each organism that specify the sequence of amino acids in proteins characteristic of that organism. As a basis for understanding this concept:
P.O. Book & Chapter page no.s
a. Students know the general pathway by which ribosomes synthesize proteins, using tRNAs to translate genetic information in mRNA.
SB1: Molecular Genetics 153, 158
b. Students know how to apply the genetic coding rules to predict the sequence of amino acids from a sequence of codons in RNA.
SB1: Molecular Genetics 146
c. Students know how mutations in the DNA sequence of a gene may or may not affect the expression of the gene or the sequence of amino acids in an encoded protein.
SB1: Genes & Chromosomes 189-198
d. Students know specialization of cells in multicellular organisms is usually due to different patterns of gene expression rather than to differences of the genes themselves.
SB1: Cell Structure 103-104, 107, 108
SB1: Molecular Genetics 155-156
e. Students know proteins can differ from one another in the number and sequence of amino acids.
SB1: The Chemistry of Life 65-68
f.* Students know why proteins having different amino acid sequences typically have different shapes and chemical properties.
SB1: The Chemistry of Life 67-68
 
5. The genetic composition of cells can be altered by incorporation of exogenous DNA into the cells. As a basis for understanding this concept:
P.O. Book & Chapter page no.s
a. Students know the general structures and functions of DNA, RNA, and protein.
SB1: The Chemistry of Life 67-68
SB1: Molecular Genetics 143-153, 157-158, 164
b. Students know how to apply base-pairing rules to explain precise copying of DNA during semiconservative replication and transcription of information from DNA into mRNA.
SB1: Molecular Genetics 143-144, 147-150
c. Students know how genetic engineering (biotechnology) is used to produce novel biomedical and agricultural products.
SB1: GeneTechnology 241-242, 257, 260
SB2: Microbes & Biotechnology 386-387, 391-392
d.* Students know how basic DNA technology (restriction digestion by endonucleases, gel electrophoresis, ligation, and transformation) is used to construct recombinant DNA molecules.
SB1: GeneTechnology 243-254
e.* Students know how exogenous DNA can be inserted into bacterial cells to alter their genetic makeup and support expression of new protein products.
SB1: GeneTechnology 255-256
SB2: Microbes & Biotechnology 386, 391-392
     

Ecology

   
6. Stability in an ecosystem is a balance between competing effects. As a basis for understanding this concept:
P.O. Book & Chapter page no.s
a. Students know biodiversity is the sum total of different kinds of organisms and is affected by alterations of habitats. SB1: Human Impact & Conservation 365-368, 371-381, 387, 389-390
b. Students know how to analyze changes in an ecosystem resulting from changes in climate, human activity, introduction of nonnative species, or changes in population size.
SB1: The Dynamics of Populations 309-315
SB1: Practical Ecology 347-362,
SB1: Human Impact & Conservation 365-368371-376, 380, 387
c. Students know how fluctuations in population size in an ecosystem are deter-mined by the relative rates of birth, immigration, emigration, and death.
SB1: The Dynamics of Populations 311-314, 317-318
d. Students know how water, carbon, and nitrogen cycle between abiotic resources and organic matter in the ecosystem and how oxygen cycles through photosynthesis and respiration.
SB1: Energy Flow & Nutrient Cycles 293, 297-307
e. Students know a vital part of an ecosystem is the stability of its producers and decomposers.
SB1: Energy Flow & Nutrient Cycles 294, 303-307,
SB1: Human Impact & Conservation 377-378
f. Students know at each link in a food web some energy is stored in newly made structures but much energy is dissipated into the environment as heat. This dissipation may be represented in an energy pyramid.
SB1: Energy Flow & Nutrient Cycles 293-302
g.* Students know how to distinguish between the accommodation of an individual organism to its environment and the gradual adaptation of a lineage of organisms through genetic change.
SB1: Ecosystems 287-288
SB2: Speciation 97, 99-100, 103-104
     
Evolution    
7. The frequency of an allele in a gene pool of a population depends on many factors and may be stable or unstable over time. As a basis for understanding this concept:
P.O. Book & Chapter page no.s
a. Students know why natural selection acts on the phenotype rather than the genotype of an organism.
SB2: Speciation 98-104
b. Students know why alleles that are lethal in a homozygous individual may be carried in a heterozygote and thus maintained in a gene pool.
SB1: Genes & Chromosomes 196
SB1: Inheritance 218
SB2: Speciation 101
c. Students know new mutations are constantly being generated in a gene pool.
SB1: Genes & Chromosomes 177-180, 183-184, 189-198
SB2: Speciation 110
d. Students know variation within a species increases the likelihood that at least some members of a species will survive under changed environmental conditions.
SB1: Genes & Chromosomes 177-178, 191-192, 198
SB2: Speciation 96,
98-110
e.* Students know the conditions for Hardy-Weinberg equilibrium in a population and why these conditions are not likely to appear in nature.
SB2: Speciation 107-108, 111-114
f.* Students know how to solve the Hardy-Weinberg equation to predict the frequency of genotypes in a population, given the frequency of phenotypes.
SB2: Speciation 111-114
 
8. Evolution is the result of genetic changes that occur in constantly changing environments. As a basis for understanding this concept:
P.O. Book & Chapter page no.s
a. Students know how natural selection determines the differential survival of groups of organisms.
SB2: Speciation 98-100, 102
b. Students know a great diversity of species increases the chance that at least some organisms survive major changes in the environment.
SB2: Speciation 98, 101, 107, 109
c. Students know the effects of genetic drift on the diversity of organisms in a population.
SB2: Speciation 107, 118
d. Students know reproductive or geographic isolation affects speciation.
SB2: Speciation

116,
119-124

e. Students know how to analyze fossil evidence with regard to biological diversity, episodic speciation, and mass extinction.
SB2: The Origin & Evolution of Life 75-80
SB2: Patterns of Evolution 141
f.* Students know how to use comparative embryology, DNA or protein sequence comparisons, and other independent sources of data to create a branching diagram (cladogram) that shows probable evolutionary relationships.
SB1: Classification 329-330
SB2: The Origin & Evolution of Life 81-85
SB2: Patterns of Evolution 128
g.* Students know how several independent molecular clocks, calibrated against each other and combined with evidence from the fossil record, can help to estimate how long ago various groups of organisms diverged evolutionarily from one another.
SB2: The Origin & Evolution of Life 73-80
     
Physiology    
9. As a result of the coordinated structures and functions of organ systems, the internal environment of the human body remains relatively stable (homeostatic) despite changes in the outside environment. As a basis for understanding this concept:
P.O. Book & Chapter page no.s
a. Students know how the complementary activity of major body systems provides cells with oxygen and nutrients and removes toxic waste products such as carbon dioxide.

SB2: Diet & Animal Nutrition

 

169-170, 173-180

SB2: Gas Exchange in Animals 189-200
SB2: Animal Transport Systems 206-214
SB2: Homeostatsis & Excretion

250-252, 261-262, 270-279

b. Students know how the nervous system mediates communication between different parts of the body and the body's interactions with the environment. SB2: Homeostatsis & Excretion 250-258
SB2: Nerves, Muscles & Movement 283-285
c. Students know how feedback loops in the nervous and endocrine systems regulate conditions in the body. SB2: Homeostasis & Excretion 250, 253-254, 263
SB2: Nerves, Muscles & Movement 284-285
d. Students know the functions of the nervous system and the role of neurons in transmitting electrochemical impulses. SB2: Nerves, Muscles & Movement 284-294
e. Students know the roles of sensory neurons, interneurons, and motor neurons in sensation, thought, and response. SB2: Nerves, Muscles & Movement 287-290, 295, 303-304
f.* Students know the individual functions and sites of secretion of digestive enzymes (amylases, proteases, nucleases, lipases), stomach acid, and bile salts. SB2: Diet & Animal Nutrition 173-179
g.* Students know the homeostatic role of the kidneys in the removal of nitrogenous wastes and the role of the liver in blood detoxification and glucose balance. SB2: Homeostasis & Excretion 261-263, 271-272, 277-280
h.* Students know the cellular and molecular basis of muscle contraction, including the roles of actin, myosin, Ca+2, and ATP. SB1: Cellular Energetics 130
SB2: Nerves, Muscles & Movement 303-306
i.* Students know how hormones (including digestive, reproductive, osmoregulatory) provide internal feedback mechanisms for homeostasis at the cellular level and in whole organisms. SB2: Diet & Animal Nutrition 178-179
SB2: Reproduction & Development 232-235, 239-240, 244-247
SB2: Homeostasis & Excretion

254-260, 263,268-269, 279

 
10. Organisms have a variety of mechanisms to combat disease. As a basis for understanding the human immune response:
P.O. Book & Chapter page no.s
a. Students know the role of the skin in providing nonspecific defenses against infection. SB2: Defense Against Infectious Disease 47-48
b. Students know the role of antibodies in the body's response to infection. SB2: Defense Against Infectious Disease 57-60
c. Students know how vaccination protects an individual from infectious diseases. SB2: Defense Against Infectious Disease 61-64
d. Students know there are important differences between bacteria and viruses with respect to their requirements for growth and replication, the body's primary defenses against bacterial and viral infections, and effective treatments of these infections.
SB1: Cell Structure 87-88
SB2: Pathogens & Disease 22-26, 29-33, 41-44
SB2: Defense Against Infectious Disease 61-64
e. Students know why an individual with a compromised immune system (for example, a person with AIDS) may be unable to fight off and survive infections by microorganisms that are usually benign. SB2: Defense Against Infectious Disease 47-48, 52-53, 57-58
f.* Students know the roles of phagocytes, B-lymphocytes, and T-lymphocytes in the immune system. SB2: Defense Against Infectious Disease 53
SB2: Defense Against Infectious Disease 58-59


State: National Science Education Standards URL of standards or PDF file: http://www.nap.edu/readingroom/books/nses/html/6e.html#csg912

Standard # G - History and Nature of Science
HISTORICAL PERSPECTIVES
SB 1 or 2 Chapter page no.s
SB1 Cell Structure  
SB1 The Chemistry of Life 1
SB1 Molecular Genetics 0
SB1 Genes & Chromosomes 0
SB2 Pathogens & Disease 0
SB2 The Origin & Evolution of Life 0
SB2 The Mechanisms of Evolution 0
SB2 The Evolution of Humans 0
SB2 Animal Behavior 0
 
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